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MCM7 抗体

MCM7 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6567128
发货至: 中国
  • 抗原 See all MCM7 抗体
    MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
    适用
    • 118
    • 31
    • 25
    • 11
    • 10
    • 10
    • 9
    • 9
    • 4
    • 2
    • 1
    人, 小鼠
    宿主
    • 79
    • 37
    • 2
    克隆类型
    • 74
    • 44
    多克隆
    标记
    • 76
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MCM7 antibody is un-conjugated
    应用范围
    • 79
    • 33
    • 32
    • 22
    • 21
    • 20
    • 13
    • 13
    • 13
    • 12
    • 5
    • 5
    • 4
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    • 2
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (IF)
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human MCM7 (NP_005907.3).
    亚型
    IgG
    Top Product
    Discover our top product MCM7 Primary Antibody
  • 应用备注
    IF 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
    别名
    MCM7 (MCM7 产品)
    背景
    The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
    分子量

    Observed_MW: 81kDa

    Calculated_MW: 44kDa/60kDa/81kDa

    基因ID
    4176
    UniProt
    P33993
    途径
    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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