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Fibrillarin 抗体

This anti-Fibrillarin antibody is a 兔 多克隆 antibody detecting Fibrillarin in WB, IP 和 IF. Suitable for 人, 小鼠 和 猴.
产品编号 ABIN6567124
发货至: 中国

Quick Overview for Fibrillarin 抗体 (ABIN6567124)

抗原

See all Fibrillarin (FBL) 抗体
Fibrillarin (FBL)

适用

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  • 33
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  • 1
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人, 小鼠, 猴

宿主

  • 51
  • 10
  • 1

克隆类型

  • 47
  • 15
多克隆

标记

  • 41
  • 2
  • 1
  • 1
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  • 1
  • 1
  • 1
  • 1
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This Fibrillarin antibody is un-conjugated

应用范围

  • 53
  • 19
  • 15
  • 13
  • 13
  • 8
  • 2
  • 2
  • 1
  • 1
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  • 1
Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)
  • 纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human FBL

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000 IF 1:50 - 1:200 IP 1:50 - 1:200

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Fibrillarin (FBL)

    别名

    FBL

    背景

    Synonyms: 34 kD nucleolar scleroderma antigen,34 kDa nucleolar scleroderma antigen,Fbl,FBRL,FIB,FIB1,FLRN,Histone-glutamine methyltransferase,Nop1p,RNA U3 small nucleolar interacting protein 1,RNU3IP1,rRNA 2' O methyltransferase fibrillarin,rRNA 2'-O-methyltransferase fibrillarin

    Background: This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8 % of humans with the autoimmune disease scleroderma recognize fibrillarin.

    分子量

    Observed_MW: 36kDa

    Calculated_MW: 33kDa

    基因ID

    2091

    UniProt

    P22087

    途径

    Ribonucleoside Biosynthetic Process
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