GCLC 抗体
Quick Overview for GCLC 抗体 (ABIN6566902)
抗原
See all GCLC 抗体适用
宿主
克隆类型
标记
应用范围
- 
    - 
                                            纯化方法
- Affinity purification
- 
                                            免疫原
- Recombinant protein of human GCLC
- 
                                            亚型
- IgG
 
- 
                                            
- 
    
- 
    - 
                                            应用备注
- WB 1:500 - 1:2000
- 
                                            限制
- 仅限研究用
 
- 
                                            
- 
    - 
                                            浓度
- 1 mg/mL
- 
                                            缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 
                                            储存液
- Sodium azide
- 
                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            储存条件
- -20 °C
- 
                                            储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
 
- 
                                            
- 
    - GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))
- 
                                            别名
- GCLC
- 
                                            背景
- 
                        Synonyms: EC 6.3.2.2,Gamma ECS,Gamma glutamylcysteine synthetase,Gamma-ECS,Gamma-glutamylcysteine synthetase,GCL,Gclc,GCS,GCS heavy chain,GLCL,GLCLC,Glutamate cysteine ligase catalytic subunit,Glutamate--cysteine ligase catalytic subunit,GSH1 Background: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction. 
- 
                                            分子量
- 
                        Observed_MW: 72kDa Calculated_MW: 72kDa 
- 
                                            基因ID
- 2729
- 
                                            UniProt
- P48506
- 
                                            途径
- Cell RedoxHomeostasis
 抗原
- 
                    
 
                                     
                                     
                                    