NACA 抗体
Quick Overview for NACA 抗体 (ABIN6566781)
抗原
See all NACA (NACa1) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein of human NACA
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- NACA (NACa1) (Nascent Polypeptide Associated Complex alpha 1 (NACa1))
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别名
- NACA
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背景
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Synonyms: Alpha NAC,Alpha-NAC,Hom s 2.02,HSD48 ,MGC117224,NAC-alpha,naca,NACA/1.9.2,NACA,NACA1,Nascent polypeptide associated complex alpha polypeptide,Nascent polypeptide associated complex alpha subunit,Nascent polypeptide associated complex subunit alpha,Nascent polypeptide-associated complex subunit alpha
Background: This gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of this gene on different chromosomes.
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分子量
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Observed_MW: 37kDa, 39kDa
Calculated_MW: 23kDa/94kDa/205kDa
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基因ID
- 4666
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UniProt
- Q13765
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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