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PKN1 抗体

PKN1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6566611
发货至: 中国
  • 抗原 See all PKN1 抗体
    PKN1 (Protein Kinase N1 (PKN1))
    适用
    • 33
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 22
    • 11
    克隆类型
    • 23
    • 10
    多克隆
    标记
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PKN1 antibody is un-conjugated
    应用范围
    • 18
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human PKN1
    亚型
    IgG
    Top Product
    Discover our top product PKN1 Primary Antibody
  • 应用备注
    WB 1:500 - 1:1000 IHC 1:50 - 1:100
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PKN1 (Protein Kinase N1 (PKN1))
    别名
    PKN1 (PKN1 产品)
    背景

    Synonyms: DBK,DPKN,PAK 1,PRK 1,PROTEIN KINASE C RELATED KINASE 1,SERINE/THREONINE PROTEIN KINASE N

    Background: The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

    分子量

    Observed_MW: 120kDa

    Calculated_MW: 104kDa

    基因ID
    5585
    UniProt
    Q16512
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