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PKN1 抗体

This 兔 多克隆 antibody specifically detects PKN1 in WB 和 IHC. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN6566611
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PKN1 抗体 (ABIN6566611)

抗原

See all PKN1 抗体
PKN1 (Protein Kinase N1 (PKN1))

适用

  • 35
  • 9
  • 7
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 24
  • 11

克隆类型

  • 24
  • 11
多克隆

标记

  • 21
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This PKN1 antibody is un-conjugated

应用范围

  • 19
  • 8
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human PKN1

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:1000 IHC 1:50 - 1:100

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    PKN1 (Protein Kinase N1 (PKN1))

    别名

    PKN1

    背景

    Synonyms: DBK,DPKN,PAK 1,PRK 1,PROTEIN KINASE C RELATED KINASE 1,SERINE/THREONINE PROTEIN KINASE N

    Background: The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

    分子量

    Observed_MW: 120kDa

    Calculated_MW: 104kDa

    基因ID

    5585

    UniProt

    Q16512
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