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CARD8 抗体

This anti-CARD8 antibody is a 兔 多克隆 antibody detecting CARD8 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6566566
发货至: 中国

Quick Overview for CARD8 抗体 (ABIN6566566)

抗原

See all CARD8 抗体
CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))

适用

人, 小鼠, 大鼠

宿主

  • 34
  • 5

克隆类型

  • 36
  • 3
多克隆

标记

  • 18
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CARD8 antibody is un-conjugated

应用范围

  • 31
  • 13
  • 13
  • 6
  • 6
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB)
  • 纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human CARD8

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))

    别名

    CARD8

    背景

    Synonyms: Apoptotic protein NDPP 1,Apoptotic protein NDPP1,CARD 8,CARD inhibitor of NF kappa B activating ligand,CARD inhibitor of NF kappaB activating ligand,CARD inhibitor of NF kappaB activating ligands,CARD-inhibitor of NF-kappa-B-activating ligand,CARD8,CARD8,CARDINAL,Caspase recruitment domain containing protein 8,Caspase recruitment domain family member 8,Caspase recruitment domain protein 8,Caspase recruitment domain-containing protein 8,DACAR,Dakar,DKFZp779L0366,FLJ18119,FLJ18121,KIAA0955,MGC57162,NDPP 1,NDPP,NDPP1,TUCAN,Tumor up regulated CARD containing antagonist of CASP9,Tumor up regulated CARD containing antagonist of caspase 9,Tumor up-regulated CARD-containing antagonist of CASP9,tumor up-regulated CARD-containing antagonist of caspase nine,Tumor upregulated CARD containing antagonist of CASP9

    Background: The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene.

    分子量

    Observed_MW: 55kDa

    Calculated_MW: 32kDa/44kDa/48kDa/55kDa/60kDa

    基因ID

    22900

    UniProt

    Q9Y2G2

    途径

    Positive Regulation of Endopeptidase Activity
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