IREB2 抗体 (AA 201-230)
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北京 101111
Quick Overview for IREB2 抗体 (AA 201-230) (ABIN656586)
抗原
See all IREB2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 201-230
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预测反应
- M, Pig, Rat
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This IREB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 201-230 amino acids from the Central region of human IREB2.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- IREB2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
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有效期
- 6 months
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- IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))
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别名
- IREB2
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背景
- IREB2 is a RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
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分子量
- 105059
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基因ID
- 3658
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NCBI登录号
- NP_004127
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UniProt
- P48200
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途径
- Transition Metal Ion Homeostasis
抗原
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