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Calpain 6 抗体 (AA 390-419)

This anti-Calpain 6 antibody is a 兔 多克隆 antibody detecting Calpain 6 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN656477
发货至: 中国

Quick Overview for Calpain 6 抗体 (AA 390-419) (ABIN656477)

抗原

See all Calpain 6 (CAPN6) 抗体
Calpain 6 (CAPN6)

适用

  • 31
  • 7
  • 4

宿主

  • 28
  • 4

克隆类型

  • 28
  • 4
多克隆

标记

  • 17
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Calpain 6 antibody is un-conjugated

应用范围

  • 22
  • 17
  • 16
  • 6
  • 6
  • 3
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB19561
  • 抗原表位

    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 390-419

    预测反应

    M, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This CAPN6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 390-419 amino acids from the Central region of human CAPN6.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    CAPN6 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

    有效期

    6 months
  • 抗原

    Calpain 6 (CAPN6)

    别名

    CAPN6

    背景

    Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis.

    分子量

    74576

    基因ID

    827

    NCBI登录号

    NP_055104

    UniProt

    Q9Y6Q1
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