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DVL1 抗体 (AA 442-470)

This anti-DVL1 antibody is a 兔 多克隆 antibody detecting DVL1 in WB, IF 和 IHC (p). Suitable for 人 和 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN656260
发货至: 中国

Quick Overview for DVL1 抗体 (AA 442-470) (ABIN656260)

抗原

See all DVL1 抗体
DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))

适用

  • 46
  • 31
  • 26
  • 3
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  • 3
  • 2
  • 2
  • 2
  • 1
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  • 1
人, 小鼠

宿主

  • 46
  • 2
  • 2

克隆类型

  • 50
多克隆

标记

  • 24
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DVL1 antibody is un-conjugated

应用范围

  • 43
  • 18
  • 16
  • 14
  • 13
  • 13
  • 8
  • 8
  • 4
  • 3
  • 3
  • 1
  • 1
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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB31716
  • 抗原表位

    • 16
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 442-470

    预测反应

    Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This DVL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 442-470 amino acids from the Central region of human DVL1.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:10~50. IF: 1:25. WB: 1:1000. WB: 1:2000. WB: 1:1000. IHC-P: 1:10~50. IHC-P: 1:25

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Bunn, Daniel, Rösken, ONeill, Cameron-Christie, Morgan, Brunner, Lai, Kunst, Markie, Robertson: "Mutations in DVL1 cause an osteosclerotic form of Robinow syndrome." in: American journal of human genetics, Vol. 96, Issue 4, pp. 623-30, (2015) (PubMed).

  • 抗原

    DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))

    别名

    DVL1

    背景

    DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.

    分子量

    75187

    基因ID

    1855

    NCBI登录号

    NP_004412

    UniProt

    O14640

    途径

    WNT signaling, Synaptic Membrane, Skeletal Muscle Fiber Development
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