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ELANE 抗体 (AA 28-58)

ELANE 适用: 人 WB 宿主: 兔 Polyclonal RB18822 unconjugated
产品编号 ABIN656021
发货至: 中国
  • 抗原 See all ELANE 抗体
    ELANE (Elastase, Neutrophil Expressed (ELANE))
    抗原表位
    • 16
    • 10
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 28-58
    适用
    • 86
    • 25
    • 24
    • 4
    • 1
    宿主
    • 66
    • 19
    • 4
    • 1
    克隆类型
    • 61
    • 29
    多克隆
    标记
    • 46
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ELANE antibody is un-conjugated
    应用范围
    • 53
    • 38
    • 28
    • 17
    • 13
    • 10
    • 9
    • 9
    • 7
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This Neutrophil elastase antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-58amino acids of human Neutrophil elastase.
    克隆位点
    RB18822
    亚型
    IgG
    Top Product
    Discover our top product ELANE Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    ELANE (Elastase, Neutrophil Expressed (ELANE))
    别名
    Neutrophil elastase (ELANE 产品)
    别名
    ELA2 antibody, GE antibody, HLE antibody, HNE antibody, NE antibody, PMN-E antibody, SCN1 antibody, Ela2 antibody, F430011M15Rik antibody, ela2 antibody, ELANE antibody, elastase, neutrophil expressed antibody, proteinase 3 antibody, ELANE antibody, Elane antibody, prtn3 antibody
    背景
    Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins. The product of this gene hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix following the protein's release from activated neutrophils. The enzyme may play a role in degenerative and inflammatory diseases by its proteolysis of collagen-IV and elastin of the extracellular matrix. This protein degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is clustered with other serine protease gene family members, azurocidin 1 and proteinase 3 genes, at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation.
    分子量
    28518
    基因ID
    1991
    NCBI登录号
    NP_001963
    UniProt
    P08246
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