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DDIT3 抗体 (C-Term)

This anti-DDIT3 antibody is a 兔 多克隆 antibody detecting DDIT3 in WB, IF 和 FACS. Suitable for 人 和 小鼠.
产品编号 ABIN655895
发货至: 中国

Quick Overview for DDIT3 抗体 (C-Term) (ABIN655895)

抗原

See all DDIT3 抗体
DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

适用

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人, 小鼠

宿主

  • 126
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克隆类型

  • 114
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多克隆

标记

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This DDIT3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

RB13788
  • 抗原表位

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    AA 120-149, C-Term

    预测反应

    B, Ha

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This DDIT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-149 amino acids from the C-terminal region of human DDIT3.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:10~50. WB: 1:2000. WB: 1:2000. WB: 1:1000. FC: 1:25. FC: 1:25. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

    别名

    DDIT3

    背景

    This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.

    分子量

    19175

    基因ID

    1649

    NCBI登录号

    NP_001181982, NP_001181983, NP_001181984, NP_001181986, NP_004074

    UniProt

    P35638

    途径

    Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis
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