PDE4B 抗体 (AA 189-217)
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北京 101111
Quick Overview for PDE4B 抗体 (AA 189-217) (ABIN655630)
抗原
See all PDE4B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 189-217
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This PDE4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-217 amino acids from the Central region of human PDE4B.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))
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别名
- PDE4B
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背景
- This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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分子量
- 83343
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基因ID
- 5142
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NCBI登录号
- NP_001032416, NP_001032417, NP_001032418, NP_002591
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UniProt
- Q07343
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途径
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction
抗原
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