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PDE4B 抗体 (AA 189-217)

This anti-PDE4B antibody is a 兔 多克隆 antibody detecting PDE4B in WB 和 FACS. Suitable for 人.
产品编号 ABIN655630
发货至: 中国

Quick Overview for PDE4B 抗体 (AA 189-217) (ABIN655630)

抗原

See all PDE4B 抗体
PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))

适用

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宿主

  • 33
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  • 1

克隆类型

  • 32
  • 18
多克隆

标记

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This PDE4B antibody is un-conjugated

应用范围

  • 44
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Western Blotting (WB), Flow Cytometry (FACS)

克隆位点

RB18545
  • 抗原表位

    • 7
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    AA 189-217

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This PDE4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-217 amino acids from the Central region of human PDE4B.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))

    别名

    PDE4B

    背景

    This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

    分子量

    83343

    基因ID

    5142

    NCBI登录号

    NP_001032416, NP_001032417, NP_001032418, NP_002591

    UniProt

    Q07343

    途径

    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction
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