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CPT1C 抗体 (C-Term)

This anti-CPT1C antibody is a 兔 多克隆 antibody detecting CPT1C in WB 和 FACS. Suitable for 人.
产品编号 ABIN655406
发货至: 中国

Quick Overview for CPT1C 抗体 (C-Term) (ABIN655406)

抗原

See all CPT1C 抗体
CPT1C (Carnitine Palmitoyltransferase 1C (CPT1C))

适用

  • 50
  • 6
  • 3

宿主

  • 51
  • 1
  • 1

克隆类型

  • 52
  • 1
多克隆

标记

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  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This CPT1C antibody is un-conjugated

应用范围

  • 38
  • 28
  • 13
  • 13
  • 8
  • 7
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS)

克隆位点

RB19024
  • 抗原表位

    • 15
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 752-782, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This CPT1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 752-782 amino acids from the C-terminal region of human CPT1C.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    CPT1C (Carnitine Palmitoyltransferase 1C (CPT1C))

    别名

    CPT1C

    背景

    The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into, and oxidation of fatty acids by, mitochondria. Malonyl-CoA, an intermediate in fatty acid synthesis, has been implicated as a regulatory component of the energy sensing system that feeds into hypothalmic neurons to impart energy homeostasis. Malonyl-CoA levels in the hypothalamus are dynamically regulated by fasting and feeding, altering subsequent feeding behaviour. Cpt1c, the brain-specific carnitine O-palmitoyltransferase 1, is thought to relay information about malonyl-CoA levels in hypothalamic neurons that express orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. Unlike other Cpt1 proteins, Cpt1c binds Malonyl-CoA but does not catalyse the transfer of the malonyl group from CoA to carnitine.

    分子量

    90989

    基因ID

    126129

    NCBI登录号

    NP_001129524, NP_001186681, NP_001186682, NP_689572

    UniProt

    Q8TCG5

    途径

    AMPK Signaling, Monocarboxylic Acid Catabolic Process
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