电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

SP1 抗体 (C-Term)

Cited in 1 publication. This anti-SP1 antibody is a 兔 多克隆 antibody detecting SP1 in WB, IF, IHC (p) 和 FACS. Suitable for 人.
产品编号 ABIN655398
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SP1 抗体 (C-Term) (ABIN655398)

抗原

See all SP1 抗体
SP1 (Sp1 Transcription Factor (SP1))

适用

  • 109
  • 61
  • 38
  • 11
  • 8
  • 7
  • 6
  • 6
  • 5
  • 5
  • 4
  • 2
  • 2
  • 2
  • 1

宿主

  • 110
  • 15
  • 3

克隆类型

  • 82
  • 46
多克隆

标记

  • 76
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SP1 antibody is un-conjugated

应用范围

  • 112
  • 59
  • 55
  • 45
  • 30
  • 18
  • 15
  • 13
  • 13
  • 12
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

克隆位点

RB17350
  • 抗原表位

    • 21
    • 12
    • 10
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 677-707, C-Term

    预测反应

    M, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This SP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 677-707 amino acids from the C-terminal region of human SP1.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:10~50. WB: 1:500. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Zhang, Wang, Qin, Liu, Sun, Liu, Kuang, Jiang, Zhang: "cis-Acting elements and trans-acting factors in the transcriptional regulation of raf kinase inhibitory protein expression." in: PLoS ONE, Vol. 8, Issue 12, pp. e83097, (2014) (PubMed).

  • 抗原

    SP1 (Sp1 Transcription Factor (SP1))

    别名

    SP1

    背景

    Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.

    分子量

    80693

    基因ID

    6667

    NCBI登录号

    NP_001238754, NP_003100, NP_612482

    UniProt

    P08047

    途径

    Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction
You are here: