KDM4C 抗体 (C-Term)
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北京 101111
Quick Overview for KDM4C 抗体 (C-Term) (ABIN655391)
抗原
See all KDM4C 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1023-1056, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This JMJD2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1023-1056 amino acids from the C-terminal region of human JMJD2C.
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亚型
- Ig Fraction
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应用备注
- WB: 1:2000. FC: 1:25. FC: 1:25
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))
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别名
- JMJD2C
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背景
- This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.
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分子量
- 119982
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基因ID
- 23081
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NCBI登录号
- NP_001140166, NP_001140167, NP_001140168, NP_055876
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UniProt
- Q9H3R0
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途径
- Nuclear Hormone Receptor Binding, Warburg Effect
抗原
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