电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Caspase 3 抗体 (C-Term)

This anti-Caspase 3 antibody is a 兔 多克隆 antibody detecting Caspase 3 in WB, IHC (p) 和 FACS. Suitable for 人.
产品编号 ABIN655271
发货至: 中国

Quick Overview for Caspase 3 抗体 (C-Term) (ABIN655271)

抗原

See all Caspase 3 (CASP3) 抗体
Caspase 3 (CASP3)

适用

  • 217
  • 127
  • 86
  • 18
  • 11
  • 8
  • 8
  • 6
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1

宿主

  • 243
  • 28
  • 3
  • 2
  • 2

克隆类型

  • 224
  • 53
多克隆

标记

  • 175
  • 21
  • 21
  • 7
  • 7
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This Caspase 3 antibody is un-conjugated

应用范围

  • 213
  • 135
  • 101
  • 64
  • 61
  • 53
  • 48
  • 36
  • 29
  • 27
  • 25
  • 10
  • 10
  • 6
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

克隆位点

RB14883
  • 抗原表位

    • 29
    • 16
    • 16
    • 14
    • 12
    • 11
    • 10
    • 9
    • 9
    • 9
    • 8
    • 8
    • 6
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 219-248, C-Term

    预测反应

    Pr, M, Rb, Rat

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This CASP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 219-248 amino acids from the C-terminal region of human CASP3.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    Caspase 3 (CASP3)

    别名

    CASP3

    背景

    This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq].

    分子量

    31608

    基因ID

    836

    NCBI登录号

    NP_004337, NP_116786

    UniProt

    P42574

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
You are here:
Chat with us!