FZD6 抗体 (AA 493-520)
Quick Overview for FZD6 抗体 (AA 493-520) (ABIN654962)
抗原
See all FZD6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 493-520
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预测反应
- M
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This FZD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 493-520 amino acids from the Central region of human FZD6.
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亚型
- Ig Fraction
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anti-Frizzled Family Receptor 6 (FZD6) (N-Term) antibody
FZD6 适用: 人, 猴 IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 6 (FZD6) (C-Term) antibodyFZD6 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 6 (FZD6) (AA 11-110) antibodyFZD6 适用: 小鼠, 大鼠 WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 6 (FZD6) antibodyFZD6 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 6 (FZD6) (AA 539-588) antibodyFZD6 适用: 人, 大鼠, 猴, Cow, 犬, 豚鼠, 马, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 6 (FZD6) (AA 19-201) antibodyFZD6 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 6 (FZD6) (AA 116-165) antibodyFZD6 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 6 (FZD6) (Extracellular Domain), (N-Term) antibodyFZD6 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- FZD6 (Frizzled Family Receptor 6 (FZD6))
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别名
- FZD6
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背景
- This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants.
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分子量
- 79292
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基因ID
- 8323
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NCBI登录号
- NP_001158087, NP_001158088, NP_003497
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UniProt
- O60353
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途径
- WNT signaling, Tube Formation
抗原
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