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ANAPC5 抗体 (AA 156-185)

This 兔 多克隆 anti-ANAPC5 antibody (Clone RB24572) specifically detects ANAPC5 in WB 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN654927
发货至: 中国
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Quick Overview for ANAPC5 抗体 (AA 156-185) (ABIN654927)

抗原

See all ANAPC5 抗体
ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))

适用

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宿主

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克隆类型

  • 54
多克隆

标记

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This ANAPC5 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS)

克隆位点

RB24572
  • 抗原表位

    • 15
    • 7
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    AA 156-185

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This ANAPC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-185 amino acids from the Central region of human ANAPC5.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))

    别名

    ANAPC5

    背景

    This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.

    分子量

    85077

    基因ID

    51433

    NCBI登录号

    NP_001131031, NP_057321

    UniProt

    Q9UJX4

    途径

    M Phase
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