CD11b 抗体 (N-Term)
Quick Overview for CD11b 抗体 (N-Term) (ABIN654625)
抗原
See all CD11b (ITGAM) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
 - AA 253-282, N-Term
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纯化方法
 - This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
 - This CD11b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-282 amino acids from the N-terminal region of human CD11b.
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亚型
 - Ig Fraction
 
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应用备注
 - WB: 1:2000. WB: 1:1000. WB: 1:500. IHC-P: 1:25. IHC-P: 1:25. IHC-P: 1:25. FC: 1:10~50
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限制
 - 仅限研究用
 
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状态
 - Liquid
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缓冲液
 - Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - 4 °C,-20 °C
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储存方法
 - Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
 - 6 months
 
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                                            : "Repetitive myocardial ischemia promotes coronary growth in the adult mammalian heart."    in: Journal of the American Heart Association, Vol. 2, Issue 5, pp. e000343, (2013)         (PubMed).        
 
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                                            : "Repetitive myocardial ischemia promotes coronary growth in the adult mammalian heart."    in: Journal of the American Heart Association, Vol. 2, Issue 5, pp. e000343, (2013)         (PubMed).        
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- CD11b (ITGAM) (Integrin alpha M (ITGAM))
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别名
 - CD11b
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背景
 - CD11b is the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.
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分子量
 - 127179
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基因ID
 - 3684
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NCBI登录号
 - NP_000623, NP_001139280
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UniProt
 - P11215
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途径
 - Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
 
抗原
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