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CD11b 抗体 (N-Term)

Cited in 1 publication. This 兔 多克隆 anti-CD11b antibody (Clone RB17991) specifically detects CD11b in FACS, WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN654625
发货至: 中国
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Quick Overview for CD11b 抗体 (N-Term) (ABIN654625)

抗原

See all CD11b (ITGAM) 抗体
CD11b (ITGAM) (Integrin alpha M (ITGAM))

适用

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克隆类型

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多克隆

标记

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This CD11b antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB17991
  • 抗原表位

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    AA 253-282, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This CD11b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-282 amino acids from the N-terminal region of human CD11b.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000. WB: 1:1000. WB: 1:500. IHC-P: 1:25. IHC-P: 1:25. IHC-P: 1:25. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Lavine, Kovacs, Weinheimer, Mann: "Repetitive myocardial ischemia promotes coronary growth in the adult mammalian heart." in: Journal of the American Heart Association, Vol. 2, Issue 5, pp. e000343, (2013) (PubMed).

  • 抗原

    CD11b (ITGAM) (Integrin alpha M (ITGAM))

    别名

    CD11b

    背景

    CD11b is the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.

    分子量

    127179

    基因ID

    3684

    NCBI登录号

    NP_000623, NP_001139280

    UniProt

    P11215

    途径

    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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