Ensa 抗体 (AA 39-66)
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北京 101111
Quick Overview for Ensa 抗体 (AA 39-66) (ABIN654413)
抗原
See all Ensa (ENSA) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 39-66
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预测反应
- B, C, Zf, Pig, Rat, X
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This ENSA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-66 amino acids from the Central region of human ENSA.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. WB: 1:1000. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- Ensa (ENSA) (Endosulfine alpha (ENSA))
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别名
- ENSA
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背景
- ENSA belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes.
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分子量
- 13389
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基因ID
- 2029
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NCBI登录号
- NP_004427, NP_996925, NP_996926, NP_996927, NP_996928, NP_996929, NP_996930, NP_997051
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UniProt
- O43768
抗原
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