Claudin 16 抗体 (N-Term)
Quick Overview for Claudin 16 抗体 (N-Term) (ABIN654394)
抗原
See all Claudin 16 (CLDN16) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 6-33, N-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This CLDN16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-33 amino acids from the N-terminal region of human CLDN16.
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亚型
- Ig Fraction
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anti-Claudin 16 (CLDN16) (AA 1-73) antibody
CLDN16 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F2 unconjugated
anti-Claudin 16 (CLDN16) (AA 1-73) antibodyCLDN16 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Claudin 16 (CLDN16) (AA 13-41), (N-Term) antibodyCLDN16 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Claudin 16 (CLDN16) (AA 6-33) antibodyCLDN16 适用: 人 WB, FACS, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Claudin 16 (CLDN16) (C-Term) antibodyCLDN16 适用: 人, 小鼠, Cow, 犬, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Claudin 16 (CLDN16) (AA 50-150) antibodyCLDN16 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Claudin 16 (CLDN16) (C-Term) antibodyCLDN16 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Claudin 16 (CLDN16) (C-Term) antibodyCLDN16 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- Claudin 16 (CLDN16)
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别名
- CLDN16
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背景
- Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is found primarily in the kidneys, specifically in the thick ascending limb of Henle, where it acts as either an intercellular pore or ion concentration sensor to regulate the paracellular resorption of magnesium ions. Defects in this gene are a cause of primary hypomagnesemia, which is characterized by massive renal magnesium wasting with hypomagnesemia and hypercalciuria, resulting in nephrocalcinosis and renal failure. This gene and the CLDN1 gene are clustered on chromosome 3q28.
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分子量
- 33836
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基因ID
- 10686
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NCBI登录号
- NP_006571
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UniProt
- Q9Y5I7
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途径
- Hepatitis C
抗原
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