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CXCR3 抗体 (AA 140-167)

Name: CXCR3 抗体 (AA 140-167)
SKU: ABIN654129
Availability: OutOfStock

This 兔多克隆 anti-CXCR3 antibody (Clone RB23384) specifically detects CXCR3 in FACS, WB 和 IHC (p). The antibody is reactive with 人 samples.

CXCR3 Antibody (Center) (ABIN654129 and ABIN2844003) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram). (CXCR3 抗体 (AA 140-167))

FACS

CXCR3 Antibody (Center) (ABIN654129 and ABIN2844003) western blot analysis in K562 cell line lysates (35 μg/lane). (CXCR3 抗体 (AA 140-167))

CXCR3 Antibody (Center) (ABIN654129 and ABIN2844003) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. (CXCR3 抗体 (AA 140-167))

IHC (p)

3 images

产品编号 ABIN654129

发货至: 中国

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中国
北京 101111

No. 88 KeChuang 6th Street

Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

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Quick Overview for CXCR3 抗体 (AA 140-167) (ABIN654129)

抗原

See all CXCR3 抗体

CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

适用

人

宿主

兔

克隆类型

多克隆

标记

This CXCR3 antibody is un-conjugated

应用范围

Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB23384

Discover our top product CXCR3 Primary Antibody

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AA 140-167

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This CXCR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-167 amino acids of human CXCR3.

亚型

IgG
anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) antibody
CXCR3 适用: 人 FACS, WB, ELISA, IHC 宿主: 小鼠 Monoclonal 5C10E6 unconjugated

anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 301-367) antibody
CXCR3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (C-Term) antibody
Verified CXCR3 适用: 人 FACS, ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 1-368) antibody
CXCR3 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 4-50) antibody
CXCR3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 1-100) antibody
CXCR3 适用: 人, 小鼠 FACS, WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) antibody
CXCR3 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) antibody
CXCR3 适用: 人 FACS, WB 宿主: 兔 Monoclonal 24GB3480 unconjugated Recombinant Antibody

anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (C-Term) antibody
CXCR3 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 147-175), (Middle Region) antibody
CXCR3 适用: 人 FACS, WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
抗原

CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

别名

CXCR3

背景

This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed IP10 (interferon-g-inducible 10 kDa protein), Mig (monokine induced by interferon-g) and I-TAC (interferon-inducible T cell a-chemoattractant). IP10, Mig and I-TAC belong to the structural subfamily of CXC chemokines, in which a single amino acid residue separates the first two of four highly conserved Cys residues. Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Inhibition by Bordetella pertussis toxin suggests that heterotrimeric G protein of the Gi-subclass couple to this protein. Signal transduction has not been further analyzed but may include the same enzymes that were identified in the signaling cascade induced by other chemokine receptors. As a consequence of chemokine-induced cellular desensitization (phosphorylation-dependent receptor internalization), cellular responses are typically rapid and short in duration. Cellular responsiveness is restored after dephosphorylation of intracellular receptors and subsequent recycling to the cell surface. This gene is prominently expressed in in vitro cultured effector/memory T cells, and in T cells present in many types of inflamed tissues. In addition, IP10, Mig and I-TAC are commonly produced by local cells in inflammatory lesion, suggesting that this gene and its chemokines participate in the recruitment of inflammatory cells. Therefore, this protein is a target for the development of small molecular weight antagonists, which may be used in the treatment of diverse inflammatory diseases. Multiple transcript variants encoding different isoforms have been found for this gene.

分子量

40660

基因ID

2833

NCBI登录号

NP_001136269, NP_001495

UniProt

P49682