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SMAD3 抗体 (AA 186-215)

This anti-SMAD3 antibody (ABIN653953) is a Rabbit Polyclonal antibody detecting SMAD3 in WB, IF, IHC (p), FACS. Suitable for Human, Mouse.
产品编号 ABIN653953
发货至: 中国

Quick Overview for SMAD3 抗体 (AA 186-215) (ABIN653953)

抗原

See all SMAD3 抗体
SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This SMAD3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

克隆位点

RB24758
  • 抗原表位

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    AA 186-215

    预测反应

    C, Pig, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This SMAD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-215 amino acids from human SMAD3.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Zhou, Liu, Pan, Du, Li, Ma, Yao, Li, Liu: "The let-7g microRNA promotes follicular granulosa cell apoptosis by targeting transforming growth factor-? type 1 receptor." in: Molecular and cellular endocrinology, Vol. 409, pp. 103-12, (2015) (PubMed).

    Lessard, Rivas, Alves-Wagner, Hirshman, Gallagher, Constantin-Teodosiu, Atkins, Greenhaff, Qi, Gustafsson, Fielding, Timmons, Britton, Koch, Goodyear: "Resistance to aerobic exercise training causes metabolic dysfunction and reveals novel exercise-regulated signaling networks." in: Diabetes, Vol. 62, Issue 8, pp. 2717-27, (2013) (PubMed).

  • 抗原

    SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))

    别名

    SMAD3

    背景

    SMAD3 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.

    分子量

    48081

    基因ID

    4088

    NCBI登录号

    NP_001138574, NP_001138575, NP_001138576, NP_005893

    UniProt

    P84022

    途径

    Cell Division Cycle, Chromatin Binding, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Autophagy
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