CDC45 抗体 (AA 236-263)
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北京 101111
Quick Overview for CDC45 抗体 (AA 236-263) (ABIN653837)
抗原
See all CDC45 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 236-263
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This CDC45L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-263 amino acids from the Central region of human CDC45L.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- CDC45 (Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45))
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别名
- CDC45L
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背景
- The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple polyadenlyation sites of this gene are reported.
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分子量
- 65569
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基因ID
- 8318
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NCBI登录号
- NP_001171481, NP_001171482, NP_003495
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UniProt
- O75419
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途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
抗原
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