TYROBP 抗体 (C-Term)
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Quick Overview for TYROBP 抗体 (C-Term) (ABIN653819)
抗原
See all TYROBP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 85-113, C-Term
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预测反应
- B
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This TYROBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-113 amino acids from the C-terminal region of human TYROBP.
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亚型
- IgG
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应用备注
- WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
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别名
- TYROBP
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背景
- TYROBP encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70 kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL.
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分子量
- 12179
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基因ID
- 7305
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NCBI登录号
- NP_001166985, NP_003323, NP_937758
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UniProt
- O43914
抗原
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