PDK2 抗体
(4 references)Quick Overview for PDK2 抗体 (ABIN653784)
抗原
See all PDK2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This PDK2 antibody is generated from rabbits immunized with recombinant protein of human PDK2.
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亚型
- Ig Fraction
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anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 187-276) antibody
PDK2 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 2G1 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 155-379) antibodyPDK2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 178-404) antibodyPDK2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 3F2D7 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (C-Term) antibodyPDK2 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 128-407) antibodyPDK2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 128-407) antibodyPDK2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 379-392), (C-Term) antibodyPDK2 适用: 人, 小鼠, 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 78-107), (N-Term) antibodyPDK2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB34663 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 378-407), (C-Term) antibodyPDK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB03037 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) antibodyPDK2 适用: 人, 小鼠 WB, IHC (p) 宿主: 小鼠 Monoclonal 7E5 unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Selective Phosphorylation Inhibitor of Delta Protein Kinase C-Pyruvate Dehydrogenase Kinase Protein-Protein Interactions: Application for Myocardial Injury in Vivo." in: Journal of the American Chemical Society, Vol. 138, Issue 24, pp. 7626-35, (2018) (PubMed).
: "Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Protein-Protein Interaction Inhibitor Reveals a Non-catalytic Role for GAPDH Oligomerization in Cell Death." in: The Journal of biological chemistry, Vol. 291, Issue 26, pp. 13608-21, (2016) (PubMed).
: "Increasing Pyruvate Dehydrogenase Flux as a Treatment for Diabetic Cardiomyopathy: A Combined 13C Hyperpolarized Magnetic Resonance and Echocardiography Study." in: Diabetes, Vol. 64, Issue 8, pp. 2735-43, (2015) (PubMed).
: "Chronic CSE treatment induces the growth of normal oral keratinocytes via PDK2 upregulation, increased glycolysis and HIF1? stabilization." in: PLoS ONE, Vol. 6, Issue 1, pp. e16207, (2011) (PubMed).
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: "Selective Phosphorylation Inhibitor of Delta Protein Kinase C-Pyruvate Dehydrogenase Kinase Protein-Protein Interactions: Application for Myocardial Injury in Vivo." in: Journal of the American Chemical Society, Vol. 138, Issue 24, pp. 7626-35, (2018) (PubMed).
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- PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))
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别名
- PDK2
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背景
- PDK2 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
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分子量
- 46154
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基因ID
- 5164
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NCBI登录号
- NP_001186827, NP_001186828, NP_002602
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UniProt
- Q15119
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途径
- PI3K-Akt Signaling, RTK signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
抗原
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