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STING/TMEM173 抗体 (C-Term)

The 兔 多克隆 anti-STING/TMEM173 antibody (Clone RB24462) (ABIN653703) specifically detects STING/TMEM173 in WB 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN653703
发货至: 中国
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Quick Overview for STING/TMEM173 抗体 (C-Term) (ABIN653703)

抗原

See all STING/TMEM173 (TMEM173) 抗体
STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

适用

  • 88
  • 33
  • 22
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 106
  • 4

克隆类型

  • 71
  • 39
多克隆

标记

  • 48
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  • 4
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  • 4
  • 4
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  • 2
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  • 1
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This STING/TMEM173 antibody is un-conjugated

应用范围

  • 74
  • 31
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  • 18
  • 13
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  • 13
  • 11
  • 3
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  • 1
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Western Blotting (WB), Flow Cytometry (FACS)

克隆位点

RB24462
  • 抗原表位

    • 18
    • 15
    • 12
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
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    • 1
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    AA 311-340, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This TMEM173 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 311-340 amino acids from the C-terminal region of human TMEM173.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

    别名

    TMEM173

    背景

    Acts as a facilitator of innate immune signaling. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.

    分子量

    42193

    基因ID

    340061

    NCBI登录号

    NP_938023

    UniProt

    Q86WV6

    途径

    Activation of Innate immune Response
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