TLR4 抗体 (AA 669-698)
Quick Overview for TLR4 抗体 (AA 669-698) (ABIN653638)
抗原
See all TLR4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 669-698
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预测反应
- B, Ha, Hs, Pig
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This TLR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 669-698 amino acids from the Central region of human TLR4.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Migration ability and Toll-like receptor expression of human mesenchymal stem cells improves significantly after three-dimensional culture." in: Biochemical and biophysical research communications, Vol. 491, Issue 2, pp. 323-328, (2017) (PubMed).
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: "Migration ability and Toll-like receptor expression of human mesenchymal stem cells improves significantly after three-dimensional culture." in: Biochemical and biophysical research communications, Vol. 491, Issue 2, pp. 323-328, (2017) (PubMed).
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- TLR4 (Toll-Like Receptor 4 (TLR4))
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别名
- TLR4
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背景
- TLR4 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes. It has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria.
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分子量
- 95680
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基因ID
- 7099
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NCBI登录号
- NP_003257, NP_612564, NP_612567
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UniProt
- O00206
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
抗原
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