CHMP4B 抗体 (N-Term)
(1 reference)Quick Overview for CHMP4B 抗体 (N-Term) (ABIN653481)
抗原
See all CHMP4B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 51-79, N-Term
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预测反应
- C, Zf, M, X
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This CHMP4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-79 amino acids from the N-terminal region of human CHMP4B.
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亚型
- Ig Fraction
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anti-Charged Multivesicular Body Protein 4B (CHMP4B) (AA 101-200) antibody
CHMP4B 适用: 人, 大鼠 ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 4B (CHMP4B) (AA 1-224) antibodyCHMP4B 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 4B (CHMP4B) antibodyCHMP4B 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 4B (CHMP4B) (N-Term) antibodyCHMP4B 适用: 人, 小鼠, 大鼠 IHC, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 4B (CHMP4B) (AA 1-224) antibodyCHMP4B 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 4B (CHMP4B) antibodyCHMP4B 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 4B (CHMP4B) (Middle Region) antibodyCHMP4B 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 4B (CHMP4B) (AA 143-192) antibodyCHMP4B 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, 小鸡, 猴, Pig IHC, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 4B (CHMP4B) (AA 71-120) antibodyCHMP4B 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, 小鸡, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "High CHMP4B expression is associated with accelerated cell proliferation and resistance to doxorubicin in hepatocellular carcinoma." in: Tumour biology, Vol. 36, Issue 4, pp. 2569-81, (2015) (PubMed).
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: "High CHMP4B expression is associated with accelerated cell proliferation and resistance to doxorubicin in hepatocellular carcinoma." in: Tumour biology, Vol. 36, Issue 4, pp. 2569-81, (2015) (PubMed).
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- CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))
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别名
- CHMP4B
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背景
- CHMP4B is a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies.
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分子量
- 24950
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基因ID
- 128866
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NCBI登录号
- NP_789782
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UniProt
- Q9H444
抗原
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