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DC-SIGN/CD209 抗体 (AA 330-355)

This anti-DC-SIGN/CD209 antibody is a 兔 多克隆 antibody detecting DC-SIGN/CD209 in WB. Suitable for 人.
产品编号 ABIN653410
发货至: 中国

Quick Overview for DC-SIGN/CD209 抗体 (AA 330-355) (ABIN653410)

抗原

See all DC-SIGN/CD209 (CD209) 抗体
DC-SIGN/CD209 (CD209) (CD209)

适用

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宿主

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克隆类型

  • 74
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多克隆

标记

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This DC-SIGN/CD209 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB21738
  • 抗原表位

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    AA 330-355

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This CD209 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 330-355 amino acids from the Central region of human CD209.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    DC-SIGN/CD209 (CD209) (CD209)

    别名

    CD209

    背景

    CD209 encodes a transmembrane receptor and is often referred to as DC-SIGN because of its expression on the surface of dendritic cells and macrophages. The encoded protein is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses with a large impact on public health. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. Variations in the number of 23 amino acid repeats in the neck domain of this protein are rare but have a significant impact on ligand binding ability. This gene is closely related in terms of both sequence and function to a neighboring gene (GeneID 10332, often referred to as L-SIGN). DC-SIGN and L-SIGN differ in their ligand-binding properties and distribution.

    分子量

    45775

    基因ID

    30835

    NCBI登录号

    NP_001138365, NP_001138366, NP_001138367, NP_001138368, NP_001138369, NP_066978

    UniProt

    Q9NNX6
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