FLIP 抗体 (AA 145-174)
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北京 101111
Quick Overview for FLIP 抗体 (AA 145-174) (ABIN653068)
抗原
See all FLIP (CFLAR) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 145-174
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This CFLAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-174 amino acids from the Central region of human CFLAR.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
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别名
- CFLAR
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背景
- Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. It acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. It lacks enzymatic (caspase) activity.
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分子量
- 55344
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基因ID
- 8837
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NCBI登录号
- NP_001120655, NP_001120656, NP_001189444, NP_001189445, NP_001189446, NP_001189447, NP_001189448, NP_003870
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UniProt
- O15519
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途径
- Apoptosis, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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