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C5 抗体 (N-Term)

This anti-C5 antibody is a 兔 多克隆 antibody detecting C5 in WB, IHC (p) 和 FACS. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN652518
发货至: 中国

Quick Overview for C5 抗体 (N-Term) (ABIN652518)

抗原

See all C5 抗体
C5 (Complement Component 5 (C5))

适用

  • 125
  • 35
  • 23
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  • 2
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  • 2

宿主

  • 117
  • 21
  • 4
  • 3

克隆类型

  • 125
  • 20
多克隆

标记

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  • 1
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This C5 antibody is un-conjugated

应用范围

  • 80
  • 50
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  • 17
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

克隆位点

RB21866
  • 抗原表位

    • 22
    • 15
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    • 11
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    • 4
    • 2
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    • 1
    • 1
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    • 1
    AA 253-281, N-Term

    特异性

    This C5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 260~289 amino acids from the N-terminal region of human C5.

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This C5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-281 AA from the N-terminal region of human C5.

    亚型

    IgG
  • 应用备注

    WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.48 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Zhang, Huang, Jing, Fu, Yuan, Xia, Cai, Gan, Chen, Zou, Long, Wang, Wang, Xu: "SAK-HV Triggered a Short-period Lipid-lowering Biotherapy Based on the Energy Model of Liver Proliferation via a Novel Pathway." in: Theranostics, Vol. 7, Issue 6, pp. 1749-1769, (2018) (PubMed).

  • 抗原

    C5 (Complement Component 5 (C5))

    别名

    C5

    背景

    C5 is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components.
    Synonyms: Complement C5, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, Complement C5 beta chain, Complement C5 alpha chain, C5a anaphylatoxin, Complement C5 alpha' chain, CPAMD4, C5

    分子量

    188305 DA

    基因ID

    727

    UniProt

    P01031

    途径

    Complement System, Carbohydrate Homeostasis
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