ADRA2B 抗体 (AA 343-369)
Quick Overview for ADRA2B 抗体 (AA 343-369) (ABIN652506)
抗原
See all ADRA2B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 343-369
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This ADRA2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-369 amino acids from the Central region of human ADRA2B.
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亚型
- IgG
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anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) (AA 349-378) antibody
ADRA2B 适用: 人 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) antibodyADRA2B 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) (AA 343-369) antibodyADRA2B 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) antibodyADRA2B 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) antibodyADRA2B 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) (AA 1-100) antibodyADRA2B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) (AA 160-174), (C169S), (Extracellular) antibodyADRA2B 适用: 大鼠 WB, FACS, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- ADRA2B (Adrenergic, alpha-2B-, Receptor (ADRA2B))
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别名
- ADRA2B
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背景
- Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Alpha 2B adrenergic receptor subtype was observed to associate with eIF-2B, a guanine nucleotide exchange protein that functions in regulation of translation. A polymorphic variant of the alpha2B subtype, which lacks 3 glutamic acids from a glutamic acid repeat element, was identified to have decreased G protein-coupled receptor kinase-mediated phosphorylation and desensitization, this polymorphic form is also associated with reduced basal metabolic rate in obese subjects and may therefore contribute to the pathogenesis of obesity. Alpha 2B adrenergic receptor gene contains no introns in either its coding or untranslated sequences.
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分子量
- 49954
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基因ID
- 151
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NCBI登录号
- NP_000673
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UniProt
- P18089
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途径
- EGFR Signaling Pathway, cAMP Metabolic Process
抗原
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