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BRSK1 抗体 (C-Term)

This anti-BRSK1 antibody is a 兔 多克隆 antibody detecting BRSK1 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN652432
发货至: 中国

Quick Overview for BRSK1 抗体 (C-Term) (ABIN652432)

抗原

See all BRSK1 抗体
BRSK1 (BR Serine/threonine Kinase 1 (BRSK1))

适用

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宿主

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克隆类型

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多克隆

标记

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This BRSK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB5415
  • 抗原表位

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    AA 654-684, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This BRSK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 654-684 amino acids from the C-terminal region of human BRSK1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    BRSK1 (BR Serine/threonine Kinase 1 (BRSK1))

    别名

    BRSK1

    背景

    BRSK1 may be involved as a checkpoint kinase in the regulation of G2/M arrest in response to UV- or methyl methane sulfonate (MMS)-induced, but not IR-induced, DNA damage. This protein phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitro and in vivo. BRSK1 is partitioned between cytoplasmic and nuclear locations in the absence of DNA damage, but translocates to the nucleus in response to Uv- or MMS-induced DNA damage. BRSK1 shares significant homology with the fission yeast Cdr2, a mitosis-regulatory kinase, and Caenorhabditis elegans SAD1, a neuronal cell polarity regulator. The BRSK1 transcript is expressed ubiquitously with the highest levels of expression in brain and testis.

    分子量

    85087

    基因ID

    84446

    NCBI登录号

    NP_115806

    UniProt

    Q8TDC3
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