PLAUR 抗体 (AA 136-166)
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北京 101111
Quick Overview for PLAUR 抗体 (AA 136-166) (ABIN652429)
抗原
See all PLAUR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 136-166
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预测反应
- Pr
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This PLAUR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-166 amino acids from the Central region of human PLAUR.
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亚型
- Ig Fraction
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anti-Plasminogen Activator, Urokinase Receptor (PLAUR) (AA 13-114) antibody
PLAUR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator, Urokinase Receptor (PLAUR) (AA 201-300) antibodyPLAUR 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator, Urokinase Receptor (PLAUR) (AA 23-305) antibodyPLAUR 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 1D1B11 unconjugated
anti-Plasminogen Activator, Urokinase Receptor (PLAUR) (AA 23-305) antibodyPLAUR 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator, Urokinase Receptor (PLAUR) antibodyKO Validated PLAUR 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator, Urokinase Receptor (PLAUR) (AA 221-305) antibodyPLAUR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator, Urokinase Receptor (PLAUR) (AA 25-134) antibodyPLAUR 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F11 unconjugated
anti-Plasminogen Activator, Urokinase Receptor (PLAUR) (AA 1-335) antibodyPLAUR 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D6 unconjugated
anti-Plasminogen Activator, Urokinase Receptor (PLAUR) antibody (PE)PLAUR 适用: 人 FACS 宿主: 小鼠 Monoclonal VIM5 PE
anti-Plasminogen Activator, Urokinase Receptor (PLAUR) (AA 13-114) antibodyPLAUR 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D4 unconjugated
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应用备注
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
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别名
- PLAUR
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背景
- The urokinase-type plasminogen activator receptor is a key molecule in the regulation of cell-surface plasminogen activation and plays an important role in many normal as well as pathologic processes. The human PLAUR cDNA encodes 335 amino acids including a predicted signal peptide of 22 residues and a hydrophobic C-terminal portion.1 It produces a highly glycosylated protein of about 50 kD in monocytes where it is anchored to the plasma membrane by glycosyl-phosphatidylinositol linkage. PLAUR, also known as UPAR, is directly associated with the carbohydrate-binding domain of SELL in the membrane of neutrophils, an association analogous to that between PLAUR and beta-2 integrins.2 PLAUR-mediated calcium mobilization is SELL dependent. UPAR mRNA levels correlate with the invasive potential of endometrial carcinomas and show a 33-fold increase in UPAR mRNA levels in advanced clinical stage endometrial tumors compared with normal endometrial tissue.3 Furthermore, the increase in UPAR mRNA levels correlated linearly with the progression of disease stage. UPAR protein expressioin correlated positively with rate of recurrence and mortality in patients with endometrial cancer.4 UPAR appears to be a useful prognostic marker for advanced endometrial cancer.
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分子量
- 36978
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基因ID
- 5329
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NCBI登录号
- NP_001005376, NP_001005377, NP_002650
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UniProt
- Q03405
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途径
- Inositol Metabolic Process
抗原
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