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GLS2 抗体 (AA 498-524)

This anti-GLS2 antibody is a 兔 多克隆 antibody detecting GLS2 in WB 和 IHC (p). Suitable for 人 和 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN652216
发货至: 中国

Quick Overview for GLS2 抗体 (AA 498-524) (ABIN652216)

抗原

See all GLS2 抗体
GLS2 (Glutaminase 2 (Liver, Mitochondrial) (GLS2))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This GLS2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB20072
  • 抗原表位

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    AA 498-524

    预测反应

    Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This GLS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 498-524 amino acids of human GLS2.

    亚型

    IgG
  • 应用备注

    WB: 1:1000. IHC-P-Leica: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Shroff, Eberlin, Dang, Gouw, Gabay, Adam, Bellovin, Tran, Philbrick, Garcia-Ocana, Casey, Li, Dang, Zare, Felsher: "MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 21, pp. 6539-44, (2015) (PubMed).

  • 抗原

    GLS2 (Glutaminase 2 (Liver, Mitochondrial) (GLS2))

    别名

    GLS2

    背景

    The protein encoded by this gene is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. This protein is functionally similar to the kidney glutaminase but is a little smaller in size. Originally thought to be liver-specific, this protein has been found in other tissues as well. At least one transcribed pseudogene has been found for this gene. [provided by RefSeq].

    分子量

    66323

    基因ID

    27165

    NCBI登录号

    NP_001267727, NP_037399

    UniProt

    Q9UI32

    途径

    Dicarboxylic Acid Transport, Warburg Effect
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