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PINK1 抗体 (C-Term)

PINK1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB6517 unconjugated
产品编号 ABIN652208
发货至: 中国
  • 抗原 See all PINK1 抗体
    PINK1 (PTEN Induced Putative Kinase 1 (PINK1))
    抗原表位
    • 21
    • 12
    • 11
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 493-526, C-Term
    适用
    • 90
    • 49
    • 24
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 71
    • 33
    • 1
    克隆类型
    • 75
    • 32
    多克隆
    标记
    • 49
    • 10
    • 9
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This PINK1 antibody is un-conjugated
    应用范围
    • 83
    • 53
    • 48
    • 18
    • 16
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This Park6(PINK1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 493-526 amino acids from the C-terminal region of human Park6(PINK1).
    克隆位点
    RB6517
    亚型
    Ig Fraction
    Top Product
    Discover our top product PINK1 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Berthier, Jiménez-Sáinz, Pulido: "PINK1 regulates histone H3 trimethylation and gene expression by interaction with the polycomb protein EED/WAIT1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 36, pp. 14729-34, (2013) (PubMed).

  • 抗原
    PINK1 (PTEN Induced Putative Kinase 1 (PINK1))
    别名
    Park6 (PINK1) (PINK1 产品)
    别名
    BEST:GH23468 antibody, CG4523 antibody, Dmel\\CG4523 antibody, PINK antibody, PINK1 antibody, dPINK1 antibody, dPink1 antibody, pink1 antibody, wu:fc39e12 antibody, zgc:101729 antibody, BRPK antibody, PARK6 antibody, 1190006F07Rik antibody, AU042772 antibody, AW557854 antibody, mFLJ00387 antibody, PTEN-induced putative kinase 1 antibody, PTEN induced putative kinase 1 antibody, Pink1 antibody, PINK1 antibody, pink1 antibody
    背景
    Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. Defects in PINK1 are the cause of autosomal recessive early-onset Parkinson's disease 6 (PARK6). Six novel pathogenic PINK1 mutations suggest that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. Strong evidence indicates that, although important in mendelian forms of Parkinson's disease (PD), PINK1 does not influence the cause of sporadic nonmendelian forms of PD.
    分子量
    62769
    基因ID
    65018
    NCBI登录号
    NP_115785
    UniProt
    Q9BXM7
    途径
    Autophagy
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