SPAG1 抗体 (N-Term)
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Quick Overview for SPAG1 抗体 (N-Term) (ABIN651886)
抗原
See all SPAG1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 124-152, N-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This SPAG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-152 amino acids from the N-terminal region of human SPAG1.
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亚型
- Ig Fraction
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anti-Sperm Associated Antigen 1 (SPAG1) (AA 1-365) antibody
SPAG1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 1 (SPAG1) antibodySPAG1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 1 (SPAG1) antibodySPAG1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 1 (SPAG1) (AA 175-283) antibodySPAG1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- SPAG1 (Sperm Associated Antigen 1 (SPAG1))
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别名
- SPAG1
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背景
- The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm agglutinating antibodies from an infertile woman. Furthermore, immunization of female rats with the recombinant human protein reduced fertility. This protein localizes to the plasma membrane of germ cells in the testis and to the post-acrosomal plasma membrane of mature spermatozoa. Recombinant polypeptide binds GTP and exhibits GTPase activity. Thus, this protein may regulate GTP signal transduction pathways involved in spermatogenesis and fertilization. Two transcript variants of this gene encode the same protein. [provided by RefSeq].
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分子量
- 103639
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基因ID
- 6674
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NCBI登录号
- NP_003105, NP_757367
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UniProt
- Q07617
抗原
-
