Cyclin D1 抗体 (AA 203-238)
Quick Overview for Cyclin D1 抗体 (AA 203-238) (ABIN651507)
抗原
See all Cyclin D1 (CCND1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
 - AA 203-238
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纯化方法
 - This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
 - This CCND1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203-238 amino acids from human CCND1.
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亚型
 - Ig Fraction
 
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应用备注
 - IF: 1:10~50. WB: 1:1000
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限制
 - 仅限研究用
 
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状态
 - Liquid
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缓冲液
 - Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - 4 °C,-20 °C
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储存方法
 - Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
 - 6 months
 
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- Cyclin D1 (CCND1)
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别名
 - CCND1
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背景
 - CCND1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb.
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分子量
 - 33729
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基因ID
 - 595
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NCBI登录号
 - NP_444284
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UniProt
 - P24385
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途径
 - PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, ER-Nucleus Signaling
 
抗原
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