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IL-4 抗体 (C-Term)

This anti-IL-4 antibody is a 兔 多克隆 antibody detecting IL-4 in WB, FACS 和 IHC (p). Suitable for 人 和 小鼠. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN651434
发货至: 中国

Quick Overview for IL-4 抗体 (C-Term) (ABIN651434)

抗原

See all IL-4 (IL4) 抗体
IL-4 (IL4) (Interleukin 4 (IL4))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This IL-4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB22885
  • 抗原表位

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    AA 122-150, AA 122-151, C-Term

    预测反应

    Pr, Sh

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This L4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-150 amino acids from the C-terminal region of human L4.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Zhang, Song, Wang, Wang, Zeng, Zhai, Ma, Li, Liao, Wang, Zhen, Wang, Cao, Lin, Ning, Liu: "Nasal IL-4(+)CXCR5(+)CD4(+) T follicular helper cell counts correlate with local IgE production in eosinophilic nasal polyps." in: The Journal of allergy and clinical immunology, Vol. 137, Issue 2, pp. 462-73, (2016) (PubMed).

    Zhong, Zhou, Wu, Guo, Tan, Zhang, Zhang, Geng, Pan, Luo, Zhang, Xu, Liu, Liu, Gao, Liu, Ren, Li, Zhou, Zhang: "A SnoRNA-derived piRNA interacts with human interleukin-4 pre-mRNA and induces its decay in nuclear exosomes." in: Nucleic acids research, Vol. 43, Issue 21, pp. 10474-91, (2015) (PubMed).

  • 抗原

    IL-4 (IL4) (Interleukin 4 (IL4))

    别名

    IL4

    背景

    IL4 is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome.

    分子量

    17492

    基因ID

    3565

    NCBI登录号

    NP_000580, NP_758858

    UniProt

    P05112

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
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