ILK 抗体 (pSer343)
Quick Overview for ILK 抗体 (pSer343) (ABIN650820)
抗原
See all ILK 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- pSer343
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预测反应
- B, M, Rat
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This ILK Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S343 of human ILK.
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亚型
- Ig Fraction
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应用备注
- DB: 1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "β1-integrin restricts astrocytic differentiation of adult hippocampal neural stem cells." in: Glia, Vol. 64, Issue 7, pp. 1235-51, (2018) (PubMed).
: "Nanofiber-mediated inhibition of focal adhesion kinase sensitizes glioma stemlike cells to epidermal growth factor receptor inhibition." in: Neuro-oncology, Vol. 15, Issue 3, pp. 319-29, (2013) (PubMed).
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: "β1-integrin restricts astrocytic differentiation of adult hippocampal neural stem cells." in: Glia, Vol. 64, Issue 7, pp. 1235-51, (2018) (PubMed).
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- ILK (Integrin-Linked Kinase (ILK))
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别名
- ILK
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背景
- Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. ILK is a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction.
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分子量
- 51419
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基因ID
- 3611
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NCBI登录号
- NP_001014794, NP_001014795, NP_001265370, NP_004508
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UniProt
- Q13418
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途径
- Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration
抗原
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