GABARAPL2 抗体
Quick Overview for GABARAPL2 抗体 (ABIN650659)
抗原
See all GABARAPL2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This GABARAPL2 antibody is generated from rabbits immunized with human GABARAPL2 recombinant protein.
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亚型
- Ig Fraction
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应用备注
- WB: 1:500. IHC-P: 1:50~100. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer." in: Nature communications, Vol. 8, pp. 14423, (2017) (PubMed).
: "Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacologic modulation." in: Experimental hematology, Vol. 43, Issue 9, pp. 781-93.e2, (2015) (PubMed).
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: "Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer." in: Nature communications, Vol. 8, pp. 14423, (2017) (PubMed).
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- GABARAPL2 (GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2))
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别名
- GABARAPL2
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背景
- Membrane proteins located on vesicles (v-SNAREs) and on the target membrane (t-SNAREs) mediate specific recognition and, possibly, fusion between a transport vesicle and its target membrane. The activity of SNARE molecules is regulated by several soluble cytosolic proteins. We have cloned a bovine brain cDNA encoding a conserved 117 amino acid polypeptide, denoted Golgi-associated ATPase Enhancer of 16 kDa (GATE-16), that functions as a soluble transport factor. GATE-16 interacts with N-ethylmaleimidesensitive factor (NSF) and significantly stimulates its ATPase activity. It also interacts with the Golgi v-SNARE GOS-28 in an NSF-dependent manner. We propose that GATE-16 modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation.
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分子量
- 13667
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基因ID
- 11345
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NCBI登录号
- NP_009216
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UniProt
- P60520
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途径
- Autophagy
抗原
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