CrkL 抗体 (pTry207)
Our Local Distributor
北京 101111
Quick Overview for CrkL 抗体 (pTry207) (ABIN645839)
抗原
See all CrkL (CRKL) 抗体适用
宿主
标记
应用范围
-
-
抗原表位
- pTry207
-
特异性
- The Goat anti-CRKL antibody detects protein derived from human recombinant protein and K562 lysate at various concentrations.
-
交叉反应
- 人, 小鼠, 大鼠
-
产品特性
- Goat Anti-CRKL
-
免疫原
- Synthetic peptide with sequence C-KIFDPQNPDENE, from the C Terminus of the protein sequence according to NP_005198, was used as immunogen.
-
亚型
- IgG
-
-
-
-
限制
- 仅限研究用
-
-
-
溶解方式
- Supplied as 100µg of purified antibody 0.5mg/ml in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin. Please avoid freeze-thaw cycles.
-
储存条件
- -20 °C
-
-
- CrkL (CRKL) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
-
别名
- CRKL
-
背景
- Anti-Crkl antibody is a 33kDa adaptor protein that has been shown to activate the RAS and JUN kinase signalling pathways. Also transforms fibroblasts in a RAS dependant manner. Crkl is a substitute of BCR ABL tyrosine kinase. In addition, Crkl has oncogenic potential, and may mediate the transduction of intracellular signals.
-
NCBI登录号
- NP_005198
-
途径
- Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor
抗原
-