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Caspase 7 抗体 (C-Term)

The 兔 多克隆 anti-Caspase 7 antibody (ABIN644997) specifically detects Caspase 7 in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN644997
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for Caspase 7 抗体 (C-Term) (ABIN644997)

抗原

See all Caspase 7 (CASP7) 抗体
Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

适用

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宿主

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克隆类型

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多克隆

标记

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This Caspase 7 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    C-Term

    原理

    Rabbit Anti-Human CASP7 (C-term)

    特异性

    DS-PB-00381 recognizes an epitope within the C-terminal region (CT) of Caspase7, a 35kDa cysteine protease, otherwise known as ICE like Apoptotic Protease 3 (ICELAP3). Caspase7, a member of the ICE/Ced3 subfamily, is an executioner caspase which undergoes proteolytic cleavage of its precursor to form active p12 and p20 subunits. Evidence that activation of Caspase7 occurs during cell death induced by the cytokine death receptors Fas/APO1 and the receptor of tumor necrosis factor (TNFR1), coupled with the fact that granzymeB activated Caspase7 cleaves the nuclear enzyme poly (ADPribose) polymerase (PARP), suggests an important role for Caspase7 in both cytokinemediated and GranzymeB mediated apoptosis pathways.

    交叉反应

    小鼠, 大鼠

    产品特性

    Phosphorylation/Apoptosis/Signal Transduction/Regulation

    纯化方法

    Purified

    免疫原

    Antisera to human Caspase-7 (CT) were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.

    亚型

    IgG
  • 应用备注

    Immunohistology - Paraffin, Western Blotting

    限制

    仅限研究用
  • 浓度

    IgG concentration 1.0 mg/ml

    缓冲液

    Phosphate buffered saline

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C
  • 抗原

    Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

    别名

    Caspase-7

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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