MICA/B 抗体
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北京 101111
Quick Overview for MICA/B 抗体 (ABIN642842)
抗原
适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse Anti-Human MICA+MICB
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特异性
- DS-MB-01916 is specific for nonclassical MHC class I chain A (MICA) and nonclassical MHC class I chain MICB (MICB). MICA and MICB are stress inducible antigens, which are closely related and appear functionally indistinguishable. MICA and MICB are ligands for NKG2D, an activating receptor on most natural killer (NK) cells, CD8 T cells and gamma delta T cells. MICA is principally expressed on intestinal epithelium, and several epithelial tumours. Expression may be induced to high surface levels by heat shock, oxidative stress, and virus infection. DS-MB-01916 is reported to inhibit the cytotoxicity of NK cells stimulated by IFN alpha-treated dendritic cells (6).
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产品特性
- MHC Class
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内毒素水平
- <0.01 EU/mg
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免疫原
- MICA transfected C1R cells
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亚型
- IgG2a
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anti-MHC Class I Polypeptide-Related Sequence A/B (MICA/MICB) antibody
MICA/MICB 适用: 人 FACS, IP, IHC 宿主: 小鼠 Monoclonal 6D4 unconjugated
anti-MHC Class I Polypeptide-Related Sequence A/B (MICA/MICB) (AA 81-180) antibodyMICA/MICB 适用: 人 IF (cc), IF (p), IHC (fro), ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MHC Class I Polypeptide-Related Sequence A/B (MICA/MICB) antibody (Biotin)MICA/MICB 适用: 人 FACS, IP, ICC 宿主: 小鼠 Monoclonal 6D4 Biotin
anti-MHC Class I Polypeptide-Related Sequence A/B (MICA/MICB) antibody (FITC)MICA/MICB 适用: 人 FACS 宿主: 小鼠 Monoclonal 6D4 FITC
anti-MHC Class I Polypeptide-Related Sequence A/B (MICA/MICB) antibody (APC)MICA/MICB 适用: 人 FACS 宿主: 小鼠 Monoclonal 6D4 APC
anti-MHC Class I Polypeptide-Related Sequence A/B (MICA/MICB) antibody (PE)MICA/MICB 适用: 人 FACS 宿主: 小鼠 Monoclonal 6D4 PE
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应用备注
- Immunohistology - Frozen, Flow Cytometry, Functional Assays, Immunoprecipitation
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限制
- 仅限研究用
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浓度
- IgG concentration 1.0 mg/ml
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缓冲液
- Phosphate buffered saline pH7.4
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储存条件
- -20 °C
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储存方法
- -20°C
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- MICA/B (MICA/MICB) (MHC Class I Polypeptide-Related Sequence A/B (MICA/MICB))
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别名
- MICA/MICB
抗原
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