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CD80 抗体 (FITC)

This anti-CD80 antibody is a 大鼠 antibody detecting CD80 in FACS. Suitable for 小鼠.
产品编号 ABIN642339
发货至: 中国

Quick Overview for CD80 抗体 (FITC) (ABIN642339)

抗原

See all CD80 抗体
CD80

适用

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小鼠

宿主

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大鼠

标记

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This CD80 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)
  • 特异性

    DS-MB-03886 recognizes mouse CD80 (B7-1), a 60kD cell surface glycoprotein which is a member of the CD28/B7 family. In mice, CD80 is expressed on monocytes, peritoneal macrophages and dendritic cells, and expression may be significantly increased upon B lymphocytes by LPS and by IL-4. CD80 has been identified as a ligand for CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4), two structurally similar molecules expressed on T cells. CD28 and CTLA4 are two receptors that have essential but opposing functions in T-cell stimulation. The Interaction of CD80 with CD28 stimulates and sustains T cell responses, whereas the interaction of CD80 with CTLA4 is reported to inhibit T-cell responses.

    产品特性

    Rat Anti-Mouse CD80, FITC-labeled

    免疫原

    BCL1 cells expressing CD80

    亚型

    IgG2a
  • 限制

    仅限研究用
  • 浓度

    IgG concentration 0.1 mg/ml

    缓冲液

    Phosphate buffered saline pH7.4

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • 抗原

    CD80

    别名

    CD80

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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