CD80 抗体 (FITC)
Quick Overview for CD80 抗体 (FITC) (ABIN642339)
抗原
See all CD80 抗体适用
宿主
标记
应用范围
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特异性
- DS-MB-03886 recognizes mouse CD80 (B7-1), a 60kD cell surface glycoprotein which is a member of the CD28/B7 family. In mice, CD80 is expressed on monocytes, peritoneal macrophages and dendritic cells, and expression may be significantly increased upon B lymphocytes by LPS and by IL-4. CD80 has been identified as a ligand for CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4), two structurally similar molecules expressed on T cells. CD28 and CTLA4 are two receptors that have essential but opposing functions in T-cell stimulation. The Interaction of CD80 with CD28 stimulates and sustains T cell responses, whereas the interaction of CD80 with CTLA4 is reported to inhibit T-cell responses.
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产品特性
- Rat Anti-Mouse CD80, FITC-labeled
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免疫原
- BCL1 cells expressing CD80
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亚型
- IgG2a
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限制
- 仅限研究用
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浓度
- IgG concentration 0.1 mg/ml
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缓冲液
- Phosphate buffered saline pH7.4
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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