DS-MB-01406 recognises the serine protease Granzyme B, which is important in the induction of apoptosis in target cells by cytolytic lymphocytes (CTLs). Granzyme B plays a key role in the induction of apoptosis by CTLs. After delivery to the target cell, Granzyme B activates the cascade of caspases that finally results in cell death. This antibody has been reported to function as a capture reagent in ELISA assays for soluble Granzyme B in conjunction with biotin conjugated DS-MB-00405 as detection reagent.