TLR7 抗体
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北京 101111
Quick Overview for TLR7 抗体 (ABIN639907)
抗原
See all TLR7 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse Anti-Human TLR7
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特异性
- DS-MB-03427 specifically recognizes human TLR7 (toll-like receptor 7), a 121 kDa type I transmembrane protein which belongs to the toll-like receptor (TLR) family, and is predominantly expressed in the spleen, lung and placenta. TLRs are highly conserved proteins which play a key role in activation of innate immunity, through the recognition of distinct molecular patterns expressed by infectious agents. TLR7 recognizes and interacts with single-stranded RNA (ssRNA) derived from viruses such as influenza , HIV-1 (human immunodeficiency virus type I) and Sendai, and some siRNAs, resulting in the activation of the MyD88/interleukin-1 receptor-associated kinase (IRAK) signaling pathway, and the production of proinflammatory signaling molecules.
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纯化方法
- Purified
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免疫原
- Recombinant human TLR7 (amino acids 451-500) purified from Escherichia coli.
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亚型
- IgG1
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anti-Toll-Like Receptor 7 (TLR7) (AA 30-230) antibody
TLR7 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 7 (TLR7) (AA 1020-1047), (C-Term) antibodyTLR7 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 7 (TLR7) (AA 461-560) antibodyTLR7 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 7 (TLR7) (AA 465-483) antibodyTLR7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 7 (TLR7) (AA 27-126) antibodyTLR7 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C9 unconjugated
anti-Toll-Like Receptor 7 (TLR7) (AA 900-950) antibodyTLR7 适用: 人, 猴 WB, IHC, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 7 (TLR7) (AA 706-728) antibody (FITC)TLR7 适用: 人, 小鼠 FACS 宿主: 兔 Polyclonal FITC
anti-Toll-Like Receptor 7 (TLR7) (AA 890-1037) antibodyTLR7 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 7 (TLR7) (AA 27-126) antibodyTLR7 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G6 unconjugated
anti-Toll-Like Receptor 7 (TLR7) (AA 706-728) antibodyTLR7 适用: 人, 小鼠 WB, IHC, FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA (dilution: 1/1000, 1/2000), Western Blotting
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限制
- 仅限研究用
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浓度
- IgG concentration 1.0 mg/ml
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缓冲液
- Phosphate buffered saline pH7.4
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C
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- TLR7 (Toll-Like Receptor 7 (TLR7))
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别名
- TLR7
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途径
- TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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