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Complement C4d 抗体

C4d 适用: 人 ELISA, IHC (fro), FACS 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN639407
发货至: 中国
  • 抗原 See all Complement C4d (C4d) products
    Complement C4d (C4d) (Complement Component C4d (C4d))
    适用
    • 33
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 26
    • 7
    小鼠
    克隆类型
    • 27
    • 6
    单克隆
    标记
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This Complement C4d antibody is un-conjugated
    应用范围
    • 21
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    • 15
    • 12
    • 10
    • 7
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)
    原理
    Mouse Anti-Human C4d (Neoantigen)
    特异性
    DS-MB-02780 recognizes a neoantigen on the secreted protein complement component 4d (C4d). The complement 1 complex cleaves complement 4 (C4) to form C4b and C4a. C4b levels are strictly regulated. Single site cleavage of the C4b's alpha chain by Factor I forms iC4b and blocks C3 convertase, inhibiting opsonization and activation of the classical pathway. This requires C4 binding protein or CR1 as a cofactor. iC4b is further degraded into C4d and C4c. The short half life of C4d means that it is present in serum at high enough concentrations to make it a useful marker for classical complement activation. C4 has been linked to susceptibility to systemic lupus erythematosous.
    产品特性
    Blood Coagulation Proteins
    纯化方法
    Purified
    免疫原
    Purified human C4d
    亚型
    IgG1
  • 应用备注
    Immunohistology - Frozen, ELISA, Flow Cytometry
    限制
    仅限研究用
  • 浓度
    IgG concentration 1.0 mg/ml
    缓冲液
    Borate buffered saline pH8.2 - 8.4
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C
  • 抗原
    Complement C4d (C4d) (Complement Component C4d (C4d))
    别名
    C4d (C4d 产品)
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