APP 抗体 (AA 1-16)
Quick Overview for APP 抗体 (AA 1-16) (ABIN6391362)
抗原
See all APP 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 1-16
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原理
- Amyloid beta peptide (aa1-16)
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序列
- DAEFRHDSGY EVHHQK
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特异性
- This antibody is expected to recognize all reported isoforms of APP (NP_000475.1, NP_958816.1, NP_958817.1, NP_001129601.1, NP_001129602.1) and to recognize all lengths of the Amyloid beta peptide.
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交叉反应
- Cow, 犬, 人, Pig
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纯化方法
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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亚型
- IgG
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应用备注
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Western Blot: Approx 75 kDa band observed in Human Brain (Cerebral and Frontal cortex) lysates (calculated MW of 78.7 kDa according to NP_958817.1 and 72.6 according to NP_001129601.1). Recommended concentration: 1-3 μg/mL. Primary incubation was 1 hour.
Peptide ELISA: antibody detection limit dilution 1:8000.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Minimize freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
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- APP (Amyloid beta (A4) Precursor Protein (APP))
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别名
- APP
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背景
- APP, amyloid beta (A4) precursor protein, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN2, OTTHUMP00000096096, PN-II, alzheimer disease amyloid protein, amyloid beta A4 protein, beta-amyloid peptide, cerebral vascular amyloid peptide, peptidase nexin-II,
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基因ID
- 351
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NCBI登录号
- NP_000475, NP_958816, NP_958817, NP_001129601, NP_001129602
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途径
- Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour
抗原
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